Basic Study on Anti-bacterial Urethral Catheter II. Potency of a New Anti-bacterial Cathete　 and Its Durability in Experimental Models

Basic Study on Anti-bacterial Urethral Catheter
２Potency of a New Anti-bacterial Cathete　 and Its Durability in Experimental Models
抗菌性尿道留置カテーテルの開発に関する基礎的研究 (第2報)
新しい抗菌性カテーテルの抗菌力と持続性

感染症学雑誌 = The journal of the Japanese Association for Infectious Diseases 74 (5), 441-449, 2000-05　東京 : 日本感染症学会

橋本英昭, 小野憲昭, 門田晃一, 公文裕巳, 斯波徹, 安達俊明, 金子佳代

The potency and effectiveness of an anti-bacterial catheter coated with a mixture of silver cit rate, soybean lecithin and liquid silicon at the ratio of 2:2:8 were compared withthose of commer cially available anti-bacterial and conventional urethral catheters. This new anti-bacterial catheter showed a strong activity and excellent durability in ordinary in vitro experimental studies. In the pre sent series we have developed new in vitro experimental models for the evaluation of anti-bacterial catheters in inhibiting bacterial ascent via intraluminal or extraluminal route. The characteristic fea tures of the silver citrate/lecithin catheter, namely strong activity and excellent durability, were con firmed using these new models that mimic urinary catheter-associated clinical infections.