Basic Study on Anti-bacterial Urethral Catheter.

抗菌性尿道留置カテーテルの開発に関する基礎的研究 (第1報) 抗菌性コーティング素材の開発
Basic Study on Anti-bacterial Urethral Catheter.
Development of a New Anti-bacterial Coating Material for Silicon Catheters.

橋本英昭, 小野憲昭, 門田晃一, 公文裕巳, 斯波徹, 安達俊明, 金子佳代

感染症学雑誌 (Journal of the Japanese Association for Infectious Diseases)
74号：5ページ： 431-440 発行年： 2000年05月20日

In order to develop a new anti-bacterial coating material suitable urethral for silicon catheters. catheter, Several we studied aspects anti-bacterial of various including anti-bacterial activity, chemical property and toxicity. silver and anti compounds Among silver cit phosphate and silver oxide, which were found to have excellent was regarded as the material of choice for anti-bacterial and biological safety. It was also found that several surfactants the surface of silicon catheters. coating inhibited anti-bacterial activities, in terms of durable ac bacterial adherence Among them soybean lecithin exhibited excellent anti-adherent ity in a dose dependent manner. Finally, a mixture to activ of silver citrate, soybean lecithin and liquid silicon at the ratio of 2:2:8 was regarded as an ideal anti-bacterial coating materialfor silicon catheters